(2017) New findings of Toll-like receptors involved in Mycobacterium tuberculosis infection. Pathogens and Global Health. pp. 256-264. ISSN 2047-7724
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Abstract
Tuberculosis (TB), an important issue in the present age, affects millions of people each year. The infectious agent of TB, Mycobacterium tuberculosis (Mtb), interacts with the immune system which prevents the development of this bacterium as much as possible. In fact, the receptors on the surface of immune cells identify the bacteria, one of which is Toll-like receptors (TLRs). Different TLRs including 2, 4, 9 and 8 play critical roles in tuberculosis infection. In this paper, we focused on the role of TLRs which interact with different components of Mtb and, consequently, prevent the entrance and influence of bacteria on the body.
| Item Type: | Article |
|---|---|
| Keywords: | Mycobacterium tuberculosis Toll-like receptors TLR immune system infection single nucleotide polymorphisms pattern-recognition receptors t-cell immunity dendritic cells pulmonary tuberculosis gene polymorphisms proinflammatory cytokines stimulates production epithelial-cells innate immunity Public, Environmental & Occupational Health Parasitology Tropical Medicine |
| Divisions: | |
| Page Range: | pp. 256-264 |
| Journal or Publication Title: | Pathogens and Global Health |
| Journal Index: | ISI |
| Volume: | 111 |
| Number: | 5 |
| Identification Number: | https://doi.org/10.1080/20477724.2017.1351080 |
| ISSN: | 2047-7724 |
| Depositing User: | مهندس مهدی شریفی |
| URI: | http://eprints.bmsu.ac.ir/id/eprint/4682 |
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