Repository of Research and Investigative Information

Repository of Research and Investigative Information

Baqiyatallah University of Medical Sciences

Study of Broad Spectrum Disinfectants Antibacterial Effect against Common Nosocomial Bacteria

(2011) Study of Broad Spectrum Disinfectants Antibacterial Effect against Common Nosocomial Bacteria. Journal of Pure and Applied Microbiology. pp. 1037-1040. ISSN 0973-7510

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Abstract

Antiseptics and disinfectants are extensively used in nosocomial systems and health care units and have important role in preventing the nosocomial infections. Resistance to these agents is very important and can cause serious problems dealing with multidrug resistant strains. The purpose of this study was to assess the in vitro activity of a group of disinfectants against nosocomial bacteria. Disc susceptibility testing is the most commonly recommended method for routine testing, and is described in the NCCLS 2004 standards. The Muller Hinton agar, Nutrient agar and Nutrient broth mediums and bacterial turbidity equal to 0.5 Mcfarland were used to assess the antimicrobial effect of Iodine, Cetrimide, Microtene 5, Formalin 37 and Deconex using disc diffusion method. The results show that Iodine had no or very low antimicrobial effect on gram negative pyogenic bacteria and no effect on acid fast and spore producing bacteria. Combination of Iodine and Cetrimide was fully synergistic against strains tested. The formalin 5 and Microten 37 had highest disc diffusion zone diameters and showed bactericidal activity on gram positive, gram negative, acid fast and sporulating bacteria. Although

Item Type: Article
Keywords: Bacteria Nosocomial Disinfectants Antibacterial activity infections Biotechnology & Applied Microbiology Microbiology
Divisions:
Page Range: pp. 1037-1040
Journal or Publication Title: Journal of Pure and Applied Microbiology
Journal Index: ISI
Volume: 5
Number: 2
ISSN: 0973-7510
Depositing User: مهندس مهدی شریفی
URI: http://eprints.bmsu.ac.ir/id/eprint/6482

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