Abstract

Mesoporous material has a significant role in medicine, health care, environmental monitoring sensing the hazardous agents and fighting against viruses and bacteria. Nano-silica sphere is an important member of the mesoporous family that noticeably flourished in biology health care and other industrial applications. Efficient one-pot multicomponent syntheses of 2-amino-3-cyano-4H-pyranderivatives ere carried out over readily available and simply synthesized recyclable Hollo Mesoporous Silica Sphere (HISS). Comparable yields were encountered with better efficiency, lower cost, and shorter reaction time. Hence. superior catalytic activity, flexibility, ease of recovery, tuneable hole size. and high surface to volume ratio ere the major characteristics of the catalyst which distinguish this protocol from previously reported ones. The catalyst as characterized by X-ray diffraction (XRD). scanning electron microscopy (SEMI). transmission electron microscopy (TEM), Fourier transform infrared (FT-IR) techniques. and nitrogen absorption and desorption (BET) analyses.The results showed that the synthesizing of HMSS catalysts under a mild and green condition in which comparable yields ere encountered with better efficiency, lower cost. and shorter reaction with other major economic advantages.