Repository of Research and Investigative Information

Repository of Research and Investigative Information

Baqiyatallah University of Medical Sciences

Electrochemical sensor based on modified methylcellulose by graphene oxide and Fe3O4 nanoparticles: Application in the analysis of uric acid content in urine

(2020) Electrochemical sensor based on modified methylcellulose by graphene oxide and Fe3O4 nanoparticles: Application in the analysis of uric acid content in urine. Journal of Electroanalytical Chemistry. p. 10. ISSN 1572-6657

Full text not available from this repository.

Official URL: http://apps.webofknowledge.com/InboundService.do?F...

Abstract

The modified glassy carbon electrode (GCE) with a coating containing methylcellulose/graphene oxide/iron oxide nano hydrogel (MC-GO-Fe3O4) has been developed to design a high-performance electrochemical bioassay system. The influence of each component of the modifier was investigated separately. This comparison showed that exist of all components in modification has a synergistic effect. MC-GO-Fe3O4 nanocomposite has a larger surface area and provides a more fine-grained media to facilitate electron transfer during the reaction between analyte and electrode. The modified GCE. was used for the electrooxidation of uric acid (UA) as a model analyte by differential pulse voltammetry (DPV) and cyclic voltammetry (CV) techniques. It exhibits a diffusion-controlled process with a two-electron, twoproton transfer reaction. The ability of the developed electrode to measure UA was studied and it has been found a linear dependence on UA concentration with a linear amplitude of 0.5-140 mu M and a limit of detection of 0.17 mu M. According to the results, the GCE vertical bar MC-GO-Fe3O4 provides an accurate and precise assay pathway of UA in the urine sample.

Item Type: Article
Keywords: Graphene oxide Glassy carbon electrode Iron oxide nanoparticles Methylcellulose Uric acid ascorbic-acid voltammetric determination biological samples mass-spectrometry dopamine surface immobilization nanocomposites tryptophan cellulose Chemistry Electrochemistry
Page Range: p. 10
Journal or Publication Title: Journal of Electroanalytical Chemistry
Journal Index: ISI
Volume: 877
Identification Number: https://doi.org/10.1016/j.jelechem.2020.114503
ISSN: 1572-6657
Depositing User: مهندس مهدی شریفی
URI: http://eprints.bmsu.ac.ir/id/eprint/8494

Actions (login required)

View Item View Item