Repository of Research and Investigative Information

Repository of Research and Investigative Information

Baqiyatallah University of Medical Sciences

Current biocompatible materials in oral regeneration: a comprehensive overview of composite materials

(2020) Current biocompatible materials in oral regeneration: a comprehensive overview of composite materials. Journal of Materials Research and Technology-Jmr&T. pp. 11731-11755. ISSN 2238-7854

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Abstract

Reconstructive orthodontics is increasingly benefiting from regenerative medicine and tissue engineering strategies. The scaffolds used both in reconstruction or in the regeneration of dental/oral defects are mainly are from two sources of materials: biologic or organic. The biologic materials have been used for regeneration and functional reconstruction of defected or lost tissues. The 3D scaffold from organic materials, including; collagen and hyaluronic acid derivatives with macromolecular properties similar to natural ECM. Bone and dentine regeneration is a growing field of research in dentistry and envisions clinical promises by improving the outcomes for the treatment of craniofacial repair and replacement. This has been recently accelerated with innovative materials and bioactive molecules and growth factors using in vitro or in vivo bioreactors. Both scaffolds made from biologic and organic materials have been combined with adult stem cells with mesenchymal phenotype in a biomimicry approach to creating the more natural-like bone substitutes. This research critically reviewed the literature in the past ten years from databases (PubMed and NCBI). The review will provide an update on the impact of biologic and natural organic materials used or emerging clinically as a 3D scaffold for bone regeneration in orofacial bone defects. (C) 2020 The Authors. Published by Elsevier B.V.

Item Type: Article
Keywords: Biologic scaffolds Organic biomaterials Natural scaffolds Oral regeneration Bone regeneration demineralized bone-matrix mesenchymal stem-cells maxillary sinus augmentation anorganic bovine bone platelet-rich fibrin in-vivo evaluation hyaluronic-acid autogenous bone chitosan microparticles sustained-release Materials Science Metallurgy & Metallurgical Engineering
Page Range: pp. 11731-11755
Journal or Publication Title: Journal of Materials Research and Technology-Jmr&T
Journal Index: ISI
Volume: 9
Number: 5
Identification Number: https://doi.org/10.1016/j.jmrt.2020.08.042
ISSN: 2238-7854
Depositing User: مهندس مهدی شریفی
URI: http://eprints.bmsu.ac.ir/id/eprint/8608

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