Abstract

Bioelectrocatalysis is a phenomenon concerned with biological catalysts, which accelerates the electrochemical reactions. The bioelectrocatalysis has been widely explored by the research community in various aspects. Enzymes can catalyze different chemical reactions in living organisms by enzymes as the most important biological catalysts. These enzymatic biocatalysts are commercially available and commonly called enzyme electrodes. Electron transfer between the active center of the enzyme and the electrode can be performed either by direct electron transfer (DET) or by means of mediators (i.e. mediated electron transfer (MET)), which are discussed in details in the review presented. Therefore, different strategies have been used to increase the efficiency and stability of bioelectrocatalysis. In this review, different strategies of the bioelectrode designs are discussed and the application of the common bioelectrodes used in the biosensors are presented in the various fields. Moreover, a summary of the research status in the applications of bioelectrocatalysis in biosensors and biofuel cells was provided.