Repository of Research and Investigative Information

Repository of Research and Investigative Information

Baqiyatallah University of Medical Sciences

Changes in the Epidemiology of Cutaneous Leishmaniasis in Northeastern Iran

(2020) Changes in the Epidemiology of Cutaneous Leishmaniasis in Northeastern Iran. Turkiye parazitolojii dergisi. pp. 52-57. ISSN 1300-6320

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Official URL: http://www.ncbi.nlm.nih.gov/pubmed/32212595

Abstract

The province of Khorasan-Razavi in the North East of Iran is an endemic area for anthroponotic cutaneous leishmaniasis (ACL caused mainly by Leishmania tropica) and zoonotic cutaneous leishmaniasis (ZCL caused mainly by Leishmania major). Based on clinical signs, some cities were considered as ACL foci while others were considered to be endemic for ZCL. This paper reviews studies performed on patients diagnosed with cutaneous leishmaniasis (CL) via the use of direct slide examination, ELISA, electrophoresis isoenzyme, RAPD PCR and PCR in Mashhad; the study also includes cases of CL in other cities of the Khorasan-Razavi province where only PCR used as a diagnostic tool. The data show that both Leishmania tropica and Leishmania major caused CL in most of the cities investigated. Our review shows that Leishmania major was found in areas where ACL is prevalent and Leishmania tropica was observed in areas with high incidence of ZCL. This distribution represents a major change in the epidemiological pattern of Leishmania in the Khorasan-Razavi province.

Item Type: Article
Keywords: Adult Animals Electrophoresis/methods Enzyme-Linked Immunosorbent Assay Humans Incidence Iran/epidemiology Leishmania major/genetics/*isolation & purification Leishmania tropica/genetics/*isolation & purification Leishmaniasis, Cutaneous/diagnosis/*epidemiology/parasitology Polymerase Chain Reaction Prevalence Random Amplified Polymorphic DNA Technique Zoonoses/epidemiology/*parasitology *Cutaneous leishmaniasis *Leishmania major *Leishmania tropica *molecular and immunological techniques *Khorasan-Razavi province
Page Range: pp. 52-57
Journal or Publication Title: Turkiye parazitolojii dergisi
Journal Index: Pubmed
Volume: 44
Number: 1
Identification Number: https://doi.org/10.4274/tpd.galenos.2019.6137
ISSN: 1300-6320
Depositing User: مهندس مهدی شریفی
URI: http://eprints.bmsu.ac.ir/id/eprint/9075

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