Repository of Research and Investigative Information

Repository of Research and Investigative Information

Baqiyatallah University of Medical Sciences

A randomized comparative trial of corticosteroid phonophoresis, local corticosteroid injection, and low-level laser in the treatment of carpal tunnel syndrome

(2020) A randomized comparative trial of corticosteroid phonophoresis, local corticosteroid injection, and low-level laser in the treatment of carpal tunnel syndrome. Laser Ther. pp. 11-17. ISSN 0898-5901 (Print) 0898-5901

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Official URL: http://www.ncbi.nlm.nih.gov/pubmed/32904004

Abstract

BACKGROUND AND AIMS: Carpal tunnel syndrome is the most prevalent peripheral neuropathy and has a considerable burden on health services. We tried to compare the therapeutic effects of local corticosteroid injection, low-level laser, and corticosteroid phonophoresis in the treatment of carpal tunnel syndrome. SUBJECTS AND METHODS: We performed a randomized clinical trial with three parallel groups. The study was carried out at a University Hospital. In total, 42 participants including 31(73.8) women were randomly allocated to the treatment groups with equal sizes. We assessed pain, symptom severity and functional status with Boston Carpal Tunnel Questionnaire, and performed median nerve conduction velocity studies. Evaluations were done before the interventions and in the fourth week of study. For the group corticosteroid, under the guidance of sonography, methylprednisolone with lidocaine was injected into the carpal tunnel. For laser therapy, we administered 10 sessions, each lasting 10 seconds. We used topical hydrocortisone acetate gel 10 as the anti-inflammatory agent with phonophoresis, 3 times per week for 10 sessions. RESULTS: Within-group analyses with paired t-test showed that local corticosteroid, laser, and phonophoresis are all effective treatments. Between-group analyses with ANOVA indicated that there were significant differences among the groups after four weeks in terms of pain (p = 0.004), in favor of corticosteroid; and in sensory delay (p = 0.001), in favor of laser. For the Boston Carpal Tunnel Questionnaire and median nerve motor latency, the results were not significant. There was no important side-effect after four weeks of follow-up. CONCLUSION: The three treatments are comparable and beneficial for carpal tunnel syndrome.

Item Type: Article
Keywords: Carpal Tunnel Syndrome Corticosteroid injection Corticosteroid phonophoresis Laser therapy Median nerve
Page Range: pp. 11-17
Journal or Publication Title: Laser Ther
Journal Index: Pubmed
Volume: 29
Number: 1
Identification Number: https://doi.org/10.5978/islsm.20-OR-01
ISSN: 0898-5901 (Print) 0898-5901
Depositing User: مهندس مهدی شریفی
URI: http://eprints.bmsu.ac.ir/id/eprint/9141

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