Abstract

Background and Aim: Nursing is one of the most stressful jobs. Job stress leads to the over-formation of free radicals. Oxidative stress occurs when the balance between the production of free radicals and antioxidants is disturbed. The aim of this study was to investigate the effect of job stress on oxidative stress in nurses of selected hospitals in Sanandaj. Methods: The present study is a descriptive-analytical cross-sectional. According to the inclusion criteria, 46 nurses and 46 hospital staff entered the study. Demographic data were collected, job stress was assessed using the Osipow Job Stress Questionnaire, blood samples were prepared, and the enzymatic activity of superoxide dismutase (SOD), malondialdehyde (MDA) and catalase (CAT) were measured. Data were analyzed by SPSS software version 16. Results: There was a significant difference between the level of job stress in the group of nurses and administrative staff (P <0.05). Examination of oxidative stress parameters did not show a significant difference between the two groups for SOD enzymes (P = 0.083) and MDA (P = 0.578) and CAT (P = 0.592). Also, stress had no effect on SOD, MDA and CAT levels by modulating group variables. Conclusion: According to the research findings, job stress had no effect on oxidative stress measurement parameters. Also, the parameters of oxidative stress by modulating the stress variable did not show a significant difference between the two groups. These results may be due to the adaptation of people to stress and the same level of stress in the two groups. Further research is needed to confirm the hypotheses. © 2021 Baqiyatallah University of Medical Sciences. All rights reserved.